
Inositol is part of the vitamin B-complex. It is required for proper formation of cell membranes.
Where is it found?
Nuts, beans, wheat and wheat bran, cantaloupe, and oranges are excellent sources of inositol. Most dietary inositol is in the form of phytate.
Inositol has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
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Obsessive-compulsive disorder |
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|
Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit. |
|
Who is likely to be deficient?
Clear deficiency of inositol has not been reported, although people with diabetes have increased excretion and may benefit from inositol supplementation.
How much is usually taken?
Most people do not need to take inositol. In addition, the small amounts commonly found in multivitamin supplements are probably unnecessary and ineffective. Doctors sometimes suggest 500 mg twice per day. For depression, anxiety, and obsessive-compulsive disorder, 12–18 grams per day has been shown to be effective in double-blind trials.1 2 3 4
Are there any side effects or interactions?
Toxicity has not been reported, although people with chronic renal failure show elevated levels and should not take inositol, except under medical supervision.
Large amounts of phytate, the common dietary form of inositol, reduce the absorption of calcium, iron, and zinc. However, supplemental inositol does not have this effect.
One review article suggested that inositol may stimulate uterine contractions.5 While no research has demonstrated that inositol actually has this effect, women who are or could become pregnant should consult a doctor before taking inositol.
Are there any drug
interactions?
Certain medicines may interact with inositol. Refer to drug interactions for a list of those medicines.
References
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Copyright © 2007 Healthnotes, Inc. All rights reserved. www.healthnotes.com
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.


Reliable
and relatively consistent scientific data showing a substantial health benefit.
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