
What is it?
Phosphorus is an essential mineral that is usually found in nature combined with oxygen as phosphate. Most of the phosphate in the human body is in bone, but phosphate-containing molecules (phospholipids) are also important components of cell membranes and lipoprotein particles, such as HDL and LDL (“good” and “bad” cholesterols, respectively). Small amounts of phosphate play important roles in numerous biochemical reactions throughout the body.
Where is it found?
Phosphorus is highest in protein-rich foods and cereal grains. In addition, phosphorus additives are used in many fizzy drinks and packaged foods. Phosphorus is not often present in supplements except for certain calcium supplements, such as bone meal.
What do the advocates say?*
Phosphate is an important component of the high-energy compounds essential for muscle function, as well as compounds that participate in oxygen delivery to muscle. Phosphates can also act as acid neutralizers, which might have effects on fatigue. Some studies have shown that phosphate supplementation improves endurance performance, but others have not.
How much is usually taken by athletes?
The use of alkalinising agents, such as sodium bicarbonate, sodium citrate, and phosphate salts (potassium phosphate, sodium acid phosphate, and tribasic sodium phosphate) to enhance athletic performance is designed to neutralize the acids produced during exercise that may interfere with energy production or muscle contraction.1 Some double-blind studies, though not all, have found that sodium bicarbonate or sodium citrate typically improves exercise performance for events lasting either 1 to10 minutes or 30 to 60 minutes.2 3 4 5 6 7 8 9 10 The amounts used are 115 to 180 mg of sodium bicarbonate or 135 to 225 mg of sodium citrate per pound of body weight. These amounts are dissolved in at least two cups of fluid and are taken either as a single ingestion at least one hour before exercise or divided into smaller amounts and taken over a few hours before exercise. Performance during periods of less than one minute or between 10 and 30 minutes is not improved by taking alkalinising agents.11 12 13 14 15 Sodium citrate may be preferable to sodium bicarbonate because it causes less gastro-intestinal upset.16 Another alkalinising agent, phosphate salts, has been investigated primarily as an endurance performance enhancer, with very inconsistent results.17 18
Are there any side effects or interactions?
People with severe kidney disease must avoid excessive phosphorus. High phosphorus intake may impair absorption of iron, copper, and zinc.19 Based primarily on animal studies, some authorities have suggested that excess intake of phosphate is hazardous to normal calcium and bone metabolism,20 but this idea has been challenged.21 Phosphoric acid–containing fizzy drinks have been implicated in elevated kidney stone risk,22 23 but not all studies have found this relationship.24
Ingestion of excessive amounts of aluminium-containing antacids (such as Di-Gel®, Riopan®, Maalox®, or Mylanta®) can cause phosphorus deficiency.
Are there any drug
interactions?
Certain medicines may interact with phosphorus. Refer to drug interactions for a list of those medicines.
*Athletes and fitness advocates may claim benefits for phosphorus based on their personal or professional experience. These are individual opinions and testimonials that may or may not be supported by controlled clinical studies or published scientific articles on phosphorus. For more complete and detailed information, including references and safety information, see Phosphorus as a nutritional supplement.
References
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Copyright © 2007 Healthnotes, Inc. All rights reserved. www.healthnotes.com
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.
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